So far everything I have used from this company works, alot really depends on the person taking it, if you don't take it doesn't work out, I have noticed a difference in mood and well being going on every week I notice improvements whether it's from the conocb2 liquid or topical. Personally I prefer the topical clinical strength, it works on pain fast I have had 15 surgeries (neck and back), chronic nerve damage and a million other torn muscles but this works as fast as morphine you just don't get the rush that morphine gives but you do get the pain relief. I recently used some on my mom's diabetic neuropathy in her feet and it worked fast, it made it manageable for her to walk. Now I take cholomax + clinical strength and I do notice a change in my mood, I am usually pretty redneck because of the pain I suffer but the chocolate + gets better every day I can actually smile a little...